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Lithopone is rather nontoxic, due to the insolubility of its components. It has been used in medicine as a radiocontrast agent. Lithopone is allowed to be in contact with foodstuffs in the US and Europe.[1]
A few non-dietary studies have reported adverse effects in the gastrointestinal tract of laboratory animals given food-grade TiO2. However, these same effects were not seen when the same or higher doses of food-grade TiO2 were administered in the animals' diet. Dietary studies best reflect how humans are exposed to TiO2 from food. Thus, the Food Directorate placed the most emphasis on the results of these studies in the state of the science report.
R-895 is a paint grade titanium dioxide pigment produced by the chlorination process. Recommended for use in a variety of coating applications.
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Anatase titanium dioxide is a popular ingredient in coatings due to its excellent UV resistance and chemical stability. Many manufacturers and businesses rely on wholesale suppliers to provide high-quality anatase titanium dioxide for their coating applications.
Durabo White, 24.5 per cent zinc sulphide, 51 per cent barium sulphate, 18 per cent white clay, 5.5 per cent infusorial earth.
Lithopone
French researchers studied how and where E171 nanoparticles enter the bloodstream, first studying the route through pigs and then in vitro with human buccal cells, for a 2023 study published in the journal Nanotoxicology. The research showed that the nanoparticles absorbed quickly through the mouth and then into the bloodstream, before damaging DNA and hindering cell regeneration.
In summary, the Food Directorate's position is that there is no conclusive scientific evidence that the food additive TiO2 is a concern for human health. This is based on a review of the available scientific data relevant to food uses of TiO2. However, we will continue to monitor the emerging science on the safety of TiO2 as a food additive and may revisit our position if new scientific information becomes available.
The additive goes into a lot of personal care products to whiten and brighten colors and to make them opaque, like toothpaste and makeup.